Familial ALS Research Update

May 11, 2010

The state of research in the familial (inherited) form of ALS was the focus of a special one-hour Webinar presented by the ALS Therapy Development Institute (ALS TDI) on March 25, with reports by CEO & Chief Scientific Officer Steve Perrin.

Although familial amyotrophic lateral sclerosis (FALS) and the more common sporadic (no family history) form of the disease both progress in a similar manner once symptoms appear, the causes of sporadic ALS remain elusive, while a number of genetic mutations that cause FALS have been — and continue to be — uncovered.

Advances in technology are making it easier for scientists to probe the mechanisms that drive FALS, and the resulting new body of knowledge is revealing targets at which scientists can aim therapeutics – some of which already have moved into clinical trials specifically for FALS.

Greater understanding of the causes and potential treatments for FALS has implications for treating sporadic ALS as well.

To read the rest of the article click on this link:



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