In an article published in Nature Genetics, scientists at the ALS Therapy Development Institute (ALS TDI) describe how they have linked an unbiased gene expression profiling effort to the identification and successful preclinical testing of a potential novel therapeutic for amyotrophic lateral sclerosis (ALS).

The paper was made available via Advance Online Publication on March 28, 2010, which can be found at the Nature Genetics website by clicking here.

The work adds to the body of evidence for immune system involvement in ALS, and focuses new attention on immune system modulation as an approach for treatment.  The authors report that blocking the interaction between two immune system molecules can significantly slow disease progression in a mouse model of ALS.

To read the rest of the story, please click on this link:


The Guys Fight Night!

March 28, 2010

Niels, Rich, Chad and Keith watching the Pay Per View Fights.

And a lot of laughs with Terry and Maryann today.

A Visit and Dinner

March 27, 2010

Wenche brought soups and goodies on Friday.

A Visit

March 27, 2010

A visit on Wednesday with cousin Nick.

A Visit

March 27, 2010

A Great Visit with Patty

A Little P.T.

March 23, 2010

Keith stretching out his Dad.

A Visit

March 20, 2010

Dad and Mom came for a visit today.

A Fun Day

March 20, 2010

Nice having the kids home.

A Visit with the Kids

March 20, 2010

Keith, Kristie and Lindsey came in to visit.

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